I listened to a podcast (http://www.lullabot.com/audiocast/podcast-55-john-albin-wilkins-and-zen-...) from Lullabot (Drupal expert company) about themeing, in particular the zen theme/zengine. There are some really nice Drupal themes that look like Drupal at the zengarden http://www.mezzoblue.com/zengarden/alldesigns.

The how to on how to use the zen theme can be found on the drupal.org site http://drupal.org/project/zen