What is information?
It is the answer to the question asked.
What is a data system?
A system that holds data?
What is an information system?
A system that help you answer the question asked (often using a data system)
So... if information is the answer to the question asked, then what is the question?
A mechanism is needed to help us focus and to ask the right questions. The mechanism should allow us to focus on the things that are important in the organisation.
Does such a mechanism exist?
Yes - Theory of Constraints.
How does the mechanism work?